| 发明名称 |
METHOD FOR PREPARING INDUCED PARAXIAL MESODERM PROGENITOR (IPAM) CELLS AND THEIR USE |
| 摘要 |
The present invention relates to an ex vivo method for preparing induced paraxial mesoderm progenitor (iPAM) cells, said method comprising the step of culturing pluripotent cells in an appropriate culture medium comprising an effective amount of an activator of the Wnt signaling pathway and an effective amount of an inhibitor of the Bone Morphogenetic Protein (BMP) signaling pathway. |
| 申请公布号 |
US2014363886(A1) |
申请公布日期 |
2014.12.11 |
| 申请号 |
US201214342251 |
申请日期 |
2012.08.29 |
| 申请人 |
Pourquie Olivier;Chal Jérôme |
发明人 |
Pourquie Olivier;Chal Jérôme |
| 分类号 |
C12N5/0735;C12N5/077;C12N5/071 |
主分类号 |
C12N5/0735 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An ex vivo method for preparing induced paraxial mesoderm progenitor (iPAM) cells, said method comprising a step of culturing pluripotent cells in an appropriate culture medium comprising an effective amount of an activator of a Wnt signaling pathway. |
| 地址 |
Illkirch FR |
