发明名称 |
METHODS, ASSAYS, AND SYSTEMS RELATING TO SAKT |
摘要 |
The technology described herein is directed to methods, assays, and systems relating to determining the level of SAKT signaling activity in a sample obtained from a subject as well as methods relating to administering inhibitors and/or agonists of SAKT signaling. |
申请公布号 |
US2014363449(A1) |
申请公布日期 |
2014.12.11 |
申请号 |
US201314374434 |
申请日期 |
2013.02.20 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
Scadden David;Lee Dongjun |
分类号 |
G01N33/50;C12N15/113;C07K16/18 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating a subject having cancer, the method comprising:
determining, in a cancer cell sample obtained from the subject, the level of SAKT signaling activity; and administering a treatment to the subject; wherein a subject with a decreased level of SAKT signaling activity is administered a treatment comprising a therapeutically effective amount of an agonist of SAKT signaling; and wherein a subject with an increased level of SAKT signaling activity, as compared to a reference level, is administered a treatment comprising a therapeutically effective amount of an inhibitor of SAKT signaling. |
地址 |
Boston MA US |