| 发明名称 |
NATIVE AND AGONIST CTL EPITOPES OF THE MUC1 TUMOR ANTIGEN |
| 摘要 |
The invention provides peptides comprising a human cytolytic T lymphocyte (CTL) epitope from the human tumor-associated antigen (TAA) mucin 1 (MUC1) and analogs thereof, which can be used in vaccine prevention or therapy of cancer, as well as a nucleic acid encoding the peptide, a vector comprising the nucleic acid, a cell comprising the peptide, nucleic acid, or vector, and compositions thereof. |
| 申请公布号 |
US2014363495(A1) |
申请公布日期 |
2014.12.11 |
| 申请号 |
US201314370595 |
申请日期 |
2013.01.03 |
| 申请人 |
The United States of America, as represented by the Secretary, Department of health and human |
发明人 |
Schlom Jeffrey;Tsang Kwong-Yok |
| 分类号 |
C07K7/06;A61K35/14;A61K38/19;A61K9/127;A61K39/00;A61K45/06 |
主分类号 |
C07K7/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 5, SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 29, and SEQ ID NO: 32. |
| 地址 |
Bethesda MD US |
