| 发明名称 |
HYDROPHOBICALLY MODIFIED ANTISENSE OLIGONUCLEOTIDES COMPRISING A TRIPLE ALKYL CHAIN |
| 摘要 |
The present invention concerns an oligonucleotide modified by substitution at the 3' or the 5' end by a moiety comprising at least three saturated or unsaturated, linear or branched hydrocarbon chains comprising from 2 to 30 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer. |
| 申请公布号 |
WO2014195432(A1) |
申请公布日期 |
2014.12.11 |
| 申请号 |
WO2014EP61762 |
申请日期 |
2014.06.05 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITÉ DE BORDEAUX;UNIVERSITE D'AIX-MARSEILLE;INSTITUT JEAN PAOLI & IRENE CALMETTES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
BARTHELEMY, PHILIPPE;OUMZIL, KHALID;GISSOT, ARNAUD;ROCCHI, PALMA;ACUNZO, JULIE |
| 分类号 |
A61K9/107;A61K47/48;C12N15/11;C12N15/113 |
主分类号 |
A61K9/107 |
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