发明名称 |
PSCA: PROSTATE STEM CELL ANTIGEN AND USES THEREOF |
摘要 |
The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. |
申请公布号 |
US2014364591(A1) |
申请公布日期 |
2014.12.11 |
申请号 |
US201414297562 |
申请日期 |
2014.06.05 |
申请人 |
The Regents of the University of California ;Agensys, Inc. |
发明人 |
Reiter Robert E.;Witte Owen N.;Saffran Douglas C.;Jakobovits Aya |
分类号 |
C07K16/30 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
1. An antibody which specifically binds to PSCA on the surface of carcinoma cells, and is internalized within the carcinoma cells to which it binds. |
地址 |
Oakland CA US |