发明名称 FORMULATION AND METHOD FOR THE PREVENTION AND TREATMENT OF BONE METASTASES OR OTHER BONE DISEASES
摘要 A suspension of erythrocytes encapsulating a bisphosphonate is provided along with a method for its use for the prevention and treatment of bone metastases and other bone marrow diseases. The suspension of erythrocytes encapsulating a bisphosphonate may also be provided in which the erythrocytes have undergone a chemical treatment with an agent such as BS3 so as to promote targeting of the bone marrow. The method for the prevention and treatment of bone metastases may be accomplished by administering to a patient in need thereof of a suspension of erythrocytes encapsulating a second-generation or a third-generation bisphosphonate.
申请公布号 US2014363413(A1) 申请公布日期 2014.12.11
申请号 US201414470244 申请日期 2014.08.27
申请人 ERYTECH PHARMA 发明人 BOURGEAUX Vanessa;GODFRIN Yann
分类号 A61K47/46;A61K31/675 主分类号 A61K47/46
代理机构 代理人
主权项 1. A method for the prevention and treatment of bone metastases, comprising administering to a patient in need thereof of a suspension of erythrocytes encapsulating a second-generation or a third-generation bisphosphonate.
地址 Lyon FR