发明名称 COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT PREVENTION, AND TREATMENT OF CANCER USING PD-L1 ISOFORMS
摘要 The present invention relates to methods for identifying, assessing, preventing, and treating cancer (e.g., head, neck, and/or lung cancers in humans). A variety of PD-LI isoforni biomarkers are pro v ided, wherein alterations in the copy number of one or more of the biomarkers and/or alterations in the amount, structure, and/or acti vity of one or more of the biomarkers is associated with cancer status and indicates amenability to treatment or prevention by modulating PD-1 and/or PD-L! levels.
申请公布号 WO2014197369(A1) 申请公布日期 2014.12.11
申请号 WO2014US40504 申请日期 2014.06.02
申请人 DANA-FARBER CANCER INSTITUTE, INC. 发明人 HAMMERMAN, PETER
分类号 G01N33/50 主分类号 G01N33/50
代理机构 代理人
主权项
地址