发明名称 |
COMBINATION DEGRADABLE AND NON-DEGRADABLE MATRICES FOR ACTIVE AGENT DELIVERY |
摘要 |
<p>The present invention relates to relates to combination degradable and non-degradable matrices and related methods. In an embodiment, the invention includes an active agent delivery matrix including a degradable polymer network, a non-degradable polymer network, the non-degradable polymer network interspersed within the degradable polymer network, and an active agent. In an embodiment, the invention includes an active agent elution control matrix including a degradable polymer; and a non-degradable polymer interspersed with the degradable polymer. In an embodiment, the invention includes a method of making an active agent delivery matrix including mixing a degradable polymer with a first solvent to form a degradable polymer solution; mixing a non-degradable polymer with a second solvent to form a non-degradable polymer solution; and simultaneously depositing the degradable polymer solution and the non-degradable polymer solution onto a substrate.</p> |
申请公布号 |
EP2037882(B1) |
申请公布日期 |
2014.12.10 |
申请号 |
EP20070799132 |
申请日期 |
2007.06.28 |
申请人 |
SURMODICS, INC. |
发明人 |
CHAPPA, RALPH, A.;HERGENROTHER, ROBERT, W.;BUSHENDORF, PAULA;SLAGER, JORAM |
分类号 |
A61L27/54;A61L27/48;A61L27/58;C08L23/08;C08L33/08;C08L71/02 |
主分类号 |
A61L27/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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