发明名称 BIOINTEGRATED COMPOSITE AND METHOD FOR COATING FORMATION ON MEDICAL DEVICES WITH USE OF BIOINTEGRATED COMPOSITE
摘要 FIELD: medicine.SUBSTANCE: what is described is a biointegrated composite containing the following ingredients, wt %: collagen 5%-10%, polyazolidine ammonia modified by halogen hydrate ions 0.5%-4%, water dispersion of sub-micron flavonoid aggregates 0.5%-1%, water - the rest. What is described is a method for the coating formation, which consists in applying the biologically active composite by immersion or deposition followed by lyophilisation. The drying process is single-staged at a temperature of 3-5°C and pressure of 5×10Pa. What is also described is a method for administering the biodegradable composite into a bone cavity by separating a mucoperiosteal flap of the operated portion of the alveolar process by special taps, burs and drills forming a bone bed to be filled with a targeted osteointegration substance, mounting an implant, placing back the flap and closing the wound.EFFECT: composite has biocompatibility and haemocompatibility, optimal physical-chemical properties, as well as rapid resorbability in vivo with generating no toxic products and negative reactions when in use.3 cl, 9 dwg, 2 tbl, 4 ex
申请公布号 RU2535067(C1) 申请公布日期 2014.12.10
申请号 RU20130138555 申请日期 2013.08.19
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "SARATOVSKIJ GOSUDARSTVENNYJ AGRARNYJ UNIVERSITET IMENI N.I. VAVILOVA" 发明人 KRASNIKOV ALEKSANDR VLADIMIROVICH;ANNIKOV VJACHESLAV VASIL'EVICH;ZAJARSKIJ DMITRIJ ALEKSANDROVICH;DEREVJANCHENKO VLADIMIR VLADIMIROVICH;MOROZOVA DAR'JA DMITRIEVNA;NECHAEVA OL'GA VIKTOROVNA;ZHURVIKOV VJACHESLAV ALESEEVICH
分类号 A61L31/10;A61C8/00;A61L31/16 主分类号 A61L31/10
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