发明名称 |
Dihydrochloride salt of a tricyclic pyrazolopyrimidine derivative |
摘要 |
<p>To provide a dihydrochloride of a tricyclic pyrazolopyrimidine compound inhibiting the effect of HSP90 and a crystal thereof. The present invention provides a dihydrochloride of 2-{4-amino-2-[(3-chloro-4-methoxy-5-methylpyridin-2-yl)methyl]-2,7-dihydro-6-thia-1,2,3,5-tetraazabenzo[cd]azulen-8-yl}-N-methylacetamide which inhibits the ATPase activity of HSP90 and which has antitumor activity, a crystal thereof, a medicament comprising the same, an anticancer agent comprising the same, and the like.</p> |
申请公布号 |
EP2810945(A1) |
申请公布日期 |
2014.12.10 |
申请号 |
EP20140179253 |
申请日期 |
2011.08.22 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
MATUURA, SHINJI;KAJINO, HISAKI;NAGAI, TOMOYUKI;KOBAYASHI, KEIJIRO |
分类号 |
C07D495/16;A61K31/519;A61P35/00 |
主分类号 |
C07D495/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|