发明名称 DERIVADOS DE AMINODI-HIDROTIAZINA SUBSTITUÍDOS COM UM GRUPO CÍCLICO E SEUS USOS E COMPOSIÇÕES FARMACÊUTICAS
摘要 This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R 1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R 2a and R 2b are each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R 3a , R 3b , R 3c and R 3d are each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.; a pharmaceutically acceptable salt or solvate thereof, which is useful for treating diseases induced by production, secretion and/or deposition of amyloid ² protein.
申请公布号 BRPI0811034(A2) 申请公布日期 2014.12.09
申请号 BR2008PI11034 申请日期 2008.04.23
申请人 SHIONOGI & CO., LTD. 发明人 YUUSUKE TAMURA;SHINJI SUZUKI;YUKIO TADA;SHUJI YONEZAWA;CHIAKI FUJIKOSHI;SAE MATSUMOTO;YUUJI KOORIYAMA;TATSUHIKO UENO
分类号 C07D279/06;A61K31/497;A61K31/54;A61K31/541;A61P25/28;A61P43/00;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D495/04;C07D513/04 主分类号 C07D279/06
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