发明名称 Método para produzir uma substância alvo, e, Escherichia coli
摘要 A target substance is produced by culturing a bacterium which has the ability to produce the target substance in a medium to cause accumulation of said target substance in the medium and collecting the target substance from the medium, wherein the bacterium is modified so that a system for uptake of a byproduct of the target substance or a substrate for a biosynthesis system of the target substance into the bacterial cell. <??>In preferred embodiments, the cell uptake system is Mtr or TnaB, where activity is increased by means of genetic engineering in order to produce L-Phe and smaller amounts of L-Trp.
申请公布号 BRPI0401918(B1) 申请公布日期 2014.12.09
申请号 BR2004PI01918 申请日期 2004.06.04
申请人 AJINOMOTO CO., INC. 发明人 HISAO ITO;YOKO YAMAMOTO
分类号 C12N1/20;C12N15/01;C12N15/09;C12N15/67;C12N15/69;C12P13/22 主分类号 C12N1/20
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