| 发明名称 | Acoustically sensitive drug delivery particles comprising non-lamellar forming phosphatidylcholine | ||
| 摘要 | Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy. | ||
| 申请公布号 | US8906409(B2) | 申请公布日期 | 2014.12.09 |
| 申请号 | US201013376686 | 申请日期 | 2010.06.08 |
| 申请人 | Epitarget AS | 发明人 | Lauten Cecilia Leal;Røgnvaldsson Karen Sibylla;Fossheim Sigrid;Nilssen Esben A.;Evjen Tove J. |
| 分类号 | A61K47/24;A61K9/127;A61K9/14;A61P35/00;A61P37/00;A61P31/00;A61P29/00;B82Y5/00;A61K9/00;A61K31/704 | 主分类号 | A61K47/24 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A sonosensitive liposome having a packing parameter of P>1, comprising at least 25 mol % of a phosphatidylcholine (PC) comprising an unsaturated acyl chain of at least 20 carbon atoms or longer, wherein said liposome comprises no air bubbles or undissolved gases. | ||
| 地址 | Oslo DE | ||