发明名称 |
PROCESSO PARA O ACOPLAMENTO CATALISADO POR PALÁDIO DE ALCINAS TERMINAIS COM TOSILATOS DE HETEROARILA E BENZENOSSULFONATOS DE HETEROARILA |
摘要 |
A process for the palladium-catalyzed coupling of terminal alkynes with heteroaryl tosylates and heteroaryl benzenesulfonates The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein D, J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process of heteroaryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional heteroaryl-1-alkynes of the formula I. |
申请公布号 |
BRPI0812839(A2) |
申请公布日期 |
2014.12.09 |
申请号 |
BR2008PI12839 |
申请日期 |
2008.06.19 |
申请人 |
SANOFI-AVENTIS |
发明人 |
OMAR R'KYEK;MARC NAZARE;ANDREAS LINDENSCHMIDT;JORGE ALONSO;MATTHIAS URMANN;NIS HALLAND |
分类号 |
C07D213/127;C07D213/26;C07D213/30;C07D215/12;C07D215/14;C07D231/12;C07D231/56;C07D239/26;C07D333/24;C07D471/04 |
主分类号 |
C07D213/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|