Methods of treating vascular inflammatory disorders

摘要

Provided are methods of treating or delaying the onset of a vascular inflammatory disease (e.g., acute lung injury) in a subject including administering to the subject a therapeutically effective amount of a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1). Also provided are methods of decreasing nuclear factor-R? (NF-R?) signaling in an endothelial cell including administering to the subject a nucleic acid containing all or a part of the sequence of mature miR-181b (SEQ ID NO: 1).

主权项

1. A method of treating atherosclerosis in a subject, the method comprising:
identifying a subject in need of treatment for atherosclerosis, and administering to the subject a therapeutically effective amount of a nucleic acid comprising SEQ ID NO: 1.