| 发明名称 | Adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby | ||
| 摘要 | Adeno-associated virus 7 sequences, vectors containing same, and methods of use are provided. | ||
| 申请公布号 | US8906675(B2) | 申请公布日期 | 2014.12.09 |
| 申请号 | US200711985096 | 申请日期 | 2007.11.14 |
| 申请人 | The Trustees of the University of Pennsylvania | 发明人 | Gao Guangping;Wilson James M.;Alvira Mauricio R. |
| 分类号 | C12N15/00;C12N15/86;C07K14/005;C12N7/00;C12Q1/70 | 主分类号 | C12N15/00 |
| 代理机构 | Howson & Howson LLP | 代理人 | Howson & Howson LLP |
| 主权项 | 1. A recombinant adeno-associated virus (AAV) comprising an AAV7 vp1 capsid protein having a sequence of amino acids 1 to 737 of SEQ ID NO:2 and having packaged therein a nucleic acid molecule comprising at least one inverted terminal repeat (ITR) that has a sequence that is different than the sequence of an ITR from native AAV7. | ||
| 地址 | Philadelphia PA US | ||