| 发明名称 |
METHOD OF PREPARING AGOMELATINE COCRYSTAL AND COMPOSITION INCLUDING THE SAME |
| 摘要 |
<p>Provided in the present invention is a method for manufacturing cocrystal of agomelatine -resorcinol and agomelatine-hydroquinone by using solvent-antisolvent method, which is available of industrial mass production. The cocrystal manufactured according to the manufacturing method of the present invention shows excellent elution rate and stability in acidic and neutral medium.</p> |
| 申请公布号 |
KR101470794(B1) |
申请公布日期 |
2014.12.08 |
| 申请号 |
KR20140080808 |
申请日期 |
2014.06.30 |
| 申请人 |
SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION |
发明人 |
CHOI, GUANG JIN;LEE, MIN JEONG;CHUN, NAN HEE;SONG, KEON HYOUNG |
| 分类号 |
C07C235/16;A61K31/166;C07C231/10 |
主分类号 |
C07C235/16 |
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