发明名称 |
ANTITUMOR TERPENOID PHARMACEUTICAL COMPOSITION AMPICILLIN EXHIBITING VASCULARIZATION INHIBITORY ACTION |
摘要 |
PROBLEM TO BE SOLVED: To provide an oral pharmaceutical composition for induction of activation in an inhibition or endogenous apoptosis process of vascularization.SOLUTION: An oral pharmaceutical composition comprises an extract of Abies Sibirica from Pinaceae as a conifer, where the extract is sesquiterpenoid (3 to 6 wt.%); neutral diterpenoid (11 to 15 wt.%); diterpenic acid (23 to 28 wt.%); triterpenic acid (8 to 16 wt.%); unsaturated and saturated fatty acids (0.1 to 0.3 wt.%); a phenolic compound (0.1 to 0.2 wt.%); and monoterpenoid as the rest. The bornyl acetate content is at least 10.0% relative to the total terpene. (ii) A pharmaceutical acceptable carrier or diluent is contained. The composition is administered at a dose of 80 to 100 mg/kg body weight every day. |
申请公布号 |
JP2014224148(A) |
申请公布日期 |
2014.12.04 |
申请号 |
JP20140162970 |
申请日期 |
2014.08.08 |
申请人 |
OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU 'INITIUM-PHARM' |
发明人 |
NINA MAKSIMOVNA PINIGINA;LUDMILA ANATOLIEVNA LATSERUS;ANATOLY URIEVICH BARYSHNIKOV;FANIA IRSHATOVNA MAGANOVA;ALEKSEY MIHAILOVICH KOZLOV;ZOYA SERGEEVNA SMIRNOVNA |
分类号 |
A61K36/00;A61K9/08;A61K9/10;A61K9/107;A61K9/14;A61K9/16;A61K9/20;A61K9/48;A61K9/50;A61K9/51;A61K45/00;A61P9/14;A61P35/00;A61P35/04;A61P43/00 |
主分类号 |
A61K36/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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