发明名称 |
CRYSTAL OF RECOMBINANT INTERFERON WITH ALTERED SPATIAL CONFIGURATION, THREE-DIMENSIONAL STRUCTURE AND USES THEREOF |
摘要 |
This invention provides crystalline recombinant interferon (rSIFN-co (SEQ ID NO: 1)) having (i) the same amino acid sequence as that of human consensus interferon, and (ii) altered three-dimensional structure as compared to IFN-α2b. The interferon of the present invention exhibits enhanced biological activities. The present invention also provides a structural model of said interferon useful for drug screening and/or drug design, and mimetics of said interferon. |
申请公布号 |
US2014356324(A1) |
申请公布日期 |
2014.12.04 |
申请号 |
US201414461360 |
申请日期 |
2014.08.15 |
申请人 |
Sichuan Huiyang Life Science & Technology Corp. |
发明人 |
WEI Guangwen;Wang Dacheng |
分类号 |
C07K14/555;G06F19/00 |
主分类号 |
C07K14/555 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Chengdu CN |