METHOD FOR ESTIMATING CHANGES OF CARDIOVASCULAR INDICES USING PERIPHEAL ARTERIAL BLOOD PRESSURE WAVEFORM

摘要

The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and heat-to-beat basis. Cardiovascular indices which can be estimated include: stroke volume (SV), which being limited to, cardiac output (CO) and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods describe herein can provide a more accurate and reliable estimate of hemodynarnic parameters than existing techniques.

主权项

1. Method performed on a computer for estimating stroke volume of a cardiac cycle of a heart comprising:
a. recording an arterial blood pressure signal; b. processing with a processor the arterial blood pressure signal to obtain a plurality of parameters which are insensitive to distortions resulting from the propagation of the arterial pulse through the arterial tree; c. incorporating only the plurality of parameters which are substantially insensitive to distortion into a formula or algorithm to estimate the stroke volume of the cardiac cycle of the heart.