| 发明名称 |
METHODS AND COMPOSITIONS FOR TREATING LUPUS |
| 摘要 |
The invention relates to compositions and methods for treating lupus. The methods typically comprise the step of administrating one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA in an amount sufficient to treat the lupus; preferably by modulating cytokine expression. Preferably the compound is in an amount less than sufficient to substantially inhibit cyclin dependent kinases. |
| 申请公布号 |
US2014356373(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201414298878 |
申请日期 |
2014.06.06 |
| 申请人 |
NATROGEN THERAPEUTICS INTERNATIONAL, INC. |
发明人 |
Wang Longgui;Mencher Simon K. |
| 分类号 |
A61K31/7056;A61K45/06;A61K31/404 |
主分类号 |
A61K31/7056 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating an animal with lupus, the method comprising the step of administering to the animal in need of such treatment at least one compound selected from the group of: Meisoindigo, tri-acetylated glyco-Meisoindigo (pro-drug) or NATURA, shown as Formulas (IV), (V), and (VI) respectively, wherein the compound is administered is in an amount sufficient to treat lupus. |
| 地址 |
Valhalla NY US |
