| 摘要 |
The present invention relates to a process for the preparation of 3-amino-N-cyclopropyl-2-hydroxypropionamide derivatives as well as novel compounds prepared or used in the process. Compounds having a 3-amino-N-cyclopropyl-2-oxoalkanamide group, for example a 3-amino-N-cydopropyl-2-oxopentanamide have been shown to be useful for the treatment of hepatitis C and related disorders. 3-amino-N-cyclopropyl-2-hydroxypropionamide derivatives are intermediates useful in the synthesis of serine and cysteine inhibitors. |
