Ligand-specific inhibition of attachment of immune cells to implantable biomaterials
摘要
<p>Methods for protecting biomaterϊals comprise attaching CD47 or Ig domain thereof to the surface of the biomaterial, thereby inhibiting or reducing immune cell attachment and/or immune cell-mediated damage to the biomaterial. Also provided are kits for practicing these methods and the protected biomaterials.</p>
申请公布号
AU2010233152(B2)
申请公布日期
2014.12.04
申请号
AU20100233152
申请日期
2010.04.09
申请人
THE CHILDREN'S HOSPITAL OF PHILADELPHIA;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人
STACHELEK, STANLEY J.;DISCHER, DENNIS;LEVY, ROBERT J.;TSAI, RICHARD