发明名称 |
METHOD FOR PREPARING SIALIC ACID DERIVATIVE |
摘要 |
The present invention relates to a method for preparing a sialic acid derivative, wherein the method is characterized in that a process of using N-acetyl-D-glucosamine to prepare CMP-M-acetylneuraminic acid and a process of combining sialic acid with galactose or a galactose derivative to prepare a sialic acid (neuraminic acid) derivative are performed together in one reactor. According to the present invention, a high-priced cytidine 5'-monophosphoric acid (CMP) can be recycled in a reaction container, thereby reducing the amount of cytidine 5'-monophosphoric acid (CMP) introduced into the reaction, producing a sialic acid derivative using low-priced N-acetyl-D-glucosamine and pyruvic acid as substrates, and producing the sialic acid derivative at higher efficiency. |
申请公布号 |
WO2014193183(A1) |
申请公布日期 |
2014.12.04 |
申请号 |
WO2014KR04823 |
申请日期 |
2014.05.30 |
申请人 |
GENECHEM INC. |
发明人 |
WOO, JIN SUK;KIM, BYUNG-GEE;KIM, DAE HEE;CHOI, YUN HEE;SONG, JAE-KYUNG;KANG, SUN YOUP;SEO, WON MIN;YANG, JI YOUNG;LEE, SANG MI |
分类号 |
C12P19/00;C07H15/04;C07H15/20;C12N9/10 |
主分类号 |
C12P19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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