| 发明名称 |
Transmembrane Protein as Biosensors |
| 摘要 |
The disclosure relates to engineered transport proteins comprising at last one fluorescent reporter covalently bound to the transporter protein, wherein the transporter proteins comprise a structural inverted repeat motif, with the motif comprising a first and second subunit that are structural inverted repeats of one another and that are joined to one another by a polypeptide loop. |
| 申请公布号 |
US2014356896(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201214345529 |
申请日期 |
2012.09.18 |
| 申请人 |
Camegie Institution of Washington |
发明人 |
Frommer Wolf B.;De Michele Roberto;Ast Cindy |
| 分类号 |
G01N33/68;C07K14/415;C07K14/705 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An engineered transporter protein comprising at least one fluorescent reporter covalently bound to the transporter protein, with the transporter protein comprising a structural inverted repeat motif comprising a first and second subunit that are structural inverted repeats of one another and that are joined to one another by a polypeptide loop, wherein the at least one fluorescent reporter is covalently bound to the polypeptide loop. |
| 地址 |
Washington DC US |
