发明名称 SINGLE CHAIN INTRABODIES THAT ALTER HUNTINGTIN MUTANT DEGRADATION
摘要 Compositions and methods of use are provided for intrabodies that bind and alter the effects of poly-glutamate protein aggregation in poly-glutamate associated diseases, such as in Huntington's disease. Intrabodies are provided that prevent poly-glutamate aggregation, gene dysregulation, and negative effects of Huntington's disease.
申请公布号 CA2913418(A1) 申请公布日期 2014.12.04
申请号 CA20142913418 申请日期 2014.05.09
申请人 VYBION, INC. 发明人 HENDERSON, LEE ALAN;AMARO, IRENE ALEXANDRA
分类号 C07K16/18 主分类号 C07K16/18
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