| 发明名称 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R inhibitor |
| 摘要 |
The present invention provides methods for treating, preventing or reducing the severity of allergic reactions. The present invention also provides methods for enhancing the efficacy and/or safety of an allergen-specific immunotherapy (SIT) regimen. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4Rα) antagonist such as an anti-IL-4Rα antibody. |
| 申请公布号 |
US2014356372(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201414294544 |
申请日期 |
2014.06.03 |
| 申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
STAHL Neil;ORENGO Jamie M.;MURPHY Andrew J.;GANDHI Namita;GRAHAM Neil |
| 分类号 |
C07K16/28;A61K45/06;A61K39/395 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for treating, preventing or reducing the severity of an allergic reaction, the method comprising administering a therapeutically effective amount of a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist to a subject in need thereof. |
| 地址 |
Tarrytown NY US |
