发明名称 |
ENHANCING VESSEL LESION HOMING AND REPAIR POTENTIAL OF STEM CELLS |
摘要 |
Disclosed herein are methods of enhancing repair of vascular lesions involving the administration of cells in which TGF-β expression and/or activity has been transiently blocked. Other methods involve the administration of a TGF-β blocking agent to a subject who has a vascular lesion or is at risk of developing a vascular lesion. Alternatively, a TGF-β blocking agent and treated cells are co-administered to a subject in need thereof. |
申请公布号 |
US2014356332(A1) |
申请公布日期 |
2014.12.04 |
申请号 |
US201414271762 |
申请日期 |
2014.05.07 |
申请人 |
University of Florida Research Foundation, Inc. ;BetaStem Therapeutics, Inc. |
发明人 |
Bartelmez Stephen H.;Grant Maria B. |
分类号 |
A61K35/28;C12N5/0789;C12N15/113 |
主分类号 |
A61K35/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Gainesville FL US |