摘要 |
<p>PROBLEM TO BE SOLVED: To provide an external preparation for skin or a bio-formulation which contains synthetic peptides preservable for a long period in a biologically active condition, in an aqueous solution of the synthetic peptides of 9 or more and 20 or less amino acid sequences with bioactivity in cosmetic field, bio-field, and pharmaceutical preparation field.SOLUTION: Provided is an external preparation for skin or a bio-formulation mixed with a hyaluronic acid or biosaccharide gum and the above synthetic peptide aqueous solution. Note that cosmetics are determined as effective if the variation (reduction or increase) of the number of wrinkles are three or more in the number of each test subjects when using the following cosmetics in the figure: (a) aging premium cosmetics, (b) the aging premium cosmetics added oligopeptide-24 (0.3%) which is an EGF-like synthetic peptide, and (c) the aging premium cosmetics added oligopeptide-24 (0.3%) which is an EGF-like synthetic peptide and 10 mg/ml of hyaluronic acid.</p> |