发明名称 METHODS FOR PREVENTING OR TREATING CERTAIN DISORDERS BY INHIBITING BINDING OF IL-4 AND/OR IL-13 TO THEIR RESPECTIVE RECEPTORS
摘要 The present disclosure relates to methods of treating, ameliorating or preventing a disorder comprising administering a therapeutically effective amount of a composition comprising a protein which inhibits IL-4 and/or IL-13 from binding to their respective receptors to a subject in need thereof. In some embodiments, the disorder is preferably associated with an increase of the Th2 immune response. In some embodiments, administration is preferably locally to the lung in order to treat, ameliorate or prevent allergic asthma, rhinitis, conjunctivitis, lung fibrosis, cystic fibrosis, chronic obstructive pulmonary disease, pulmonary alveolar proteinosis or adult respiratory distress syndrome.
申请公布号 US2014357548(A1) 申请公布日期 2014.12.04
申请号 US201214364449 申请日期 2012.12.12
申请人 PIERIS AG 发明人 Hohlbaum Andreas;Audoly Laurent;Koller Beverly
分类号 A61K38/17 主分类号 A61K38/17
代理机构 代理人
主权项
地址 Freising-Wehenstephan DE