| 发明名称 |
CELL CARRIER, ASSOCIATED METHODS FOR MAKING CELL CARRIER AND CULTURING CELLS USING THE SAME |
| 摘要 |
A carrier for expansion of induced pluripotent stem cells is provided, wherein the carrier comprises a substrate comprising one or more outer surfaces, wherein the one or more outer surfaces are modified with gas plasma treatment, and one or more structured indentations on one or more of the outer surfaces. The carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm. A method of making the carrier, and culturing induced pluripotent stem cells using the same carrier are also provided. |
| 申请公布号 |
US2014356949(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201414461860 |
申请日期 |
2014.08.18 |
| 申请人 |
General Electric Company |
发明人 |
Davis Brian Michael;Conway Kenneth Roger;Loghin Evelina Roxana;Burns Andrew Arthur Paul;Gascoyne David Gilles;Miller Scott Michael |
| 分类号 |
C12N5/074 |
主分类号 |
C12N5/074 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A carrier for expansion of induced pluripotent stem cells, comprising:
a substrate comprising one or more outer surfaces; wherein the one or more outer surfaces are modified with gas plasma treatment, and wherein one or more structured indentations on one or more of the outer surfaces, and the carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.05 mm to 1.2 mm and each of the structured indentations has a major axis in a range from about 0.1 mm to 0.5 mm, a minor axis in a range from about 0.1 mm to 0.5 mm and a depth in a range from about 0.025 mm to about 0.5 mm |
| 地址 |
Schenectady NY US |
