发明名称 |
METHOD FOR DETERMINING THE RESISTANCE STATUS OF FUNGI AND YEASTS, IN PARTICULAR OF ASPERGILLUS FUMIGATUS |
摘要 |
<p>The invention relates to a method for determining the resistance status of fungi and yeasts in a body sample of a patient suspected of having an invasive infection, comprising the steps of isolating DNA from a body sample of the patient, identifying mutations in a gene of the fungus or yeast, and correlating the resistance status of the fungus or yeast to the mutations found, wherein the body sample is blood or a blood derivative or a sample of an organ, and is in particular serum. Suitably, the method is performed in closed-tube format. The method of the invention is particularly suitable when the fungus of which the resistance status is to be determined is Aspergillus fumigatus.</p> |
申请公布号 |
EP2347016(B1) |
申请公布日期 |
2014.12.03 |
申请号 |
EP20080874967 |
申请日期 |
2008.10.10 |
申请人 |
STICHTING TER BEVORDERING VAN DE FARMACODYNAMIEK |
发明人 |
KLAASSEN, CORNELIS, HENDRIKUS, WILHELM |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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