发明名称 |
PYRAZOL-1-YL BENZENE SULFONAMIDE AS CCR9 ANTAGONISTS |
摘要 |
<p>Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.</p> |
申请公布号 |
KR20140138172(A) |
申请公布日期 |
2014.12.03 |
申请号 |
KR20147026018 |
申请日期 |
2013.02.28 |
申请人 |
CHEMOCENTRYX, INC. |
发明人 |
CHEN XI;FAN JUNFA;FAN PINGCHEN;KRASINSKI ANTONI;LI LIANFA;LUI REBECCA M.;MCMAHON JEFFREY P.;POWERS JAY P.;ZENG YIBIN;ZHANG PENGLIE |
分类号 |
C07D401/04;A61K31/4709;A61K31/4725;A61P35/00;C07D403/04 |
主分类号 |
C07D401/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|