发明名称 |
TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
摘要 |
The present invention is directed to compounds of formula I and Ia: which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA. |
申请公布号 |
EP2731439(A4) |
申请公布日期 |
2014.12.03 |
申请号 |
EP20120811318 |
申请日期 |
2012.07.06 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
HANNEY, BARBARA;MANLEY, PETER;RUDD, MICHAEL, T.;SANDERS, JOHN, M.;STACHEL, SHAWN, J.;HENZE, DARRELL |
分类号 |
A01N43/90;A61K31/404;C07D471/02 |
主分类号 |
A01N43/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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