发明名称 |
COMPOSITIONS AND METHODS FOR TREATMENT OF EYE DISORDERS |
摘要 |
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In Particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists. |
申请公布号 |
EP1881823(B1) |
申请公布日期 |
2014.12.03 |
申请号 |
EP20060770607 |
申请日期 |
2006.05.17 |
申请人 |
SARCODE BIOSCIENCE INC. |
发明人 |
GADEK, THOMAS;BURNIER, JOHN |
分类号 |
A61K31/166;A61K31/198;A61K31/40;A61K31/404;A61K31/4162;A61K31/4184;A61K31/4192;A61K31/44;A61K31/4709;A61K31/4725;A61K31/4745;A61K31/496;A61K31/5377;A61K31/54;A61K31/541;A61P27/02 |
主分类号 |
A61K31/166 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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