Tracking of tumor location for targeted radiation treatment

摘要

Systems, methods, and apparatuses are provided for targeting diseased tissue with a radiation beam. Functional models can be used to accurately obtain a location of specific tissue using sensors at identifiable locations of the patient's body. Using the relative distances between the identifiable sensor locations can allow a patient to be in various positions. The functional models can be prepared using accurate pre-treatment scans, which can be taken at various body positions (e.g., rotations and/or translations). The trajectory of the beam can be measured efficiently and accurately using beam sensors attached to a beam assembly, where a model maps the beam sensor locations to a trajectory of the beam. Further, a motion model can use measurements made during treatment to obtain a time-dependent functions of the movement of the specific tissue, the change of an optimal beam trajectory over time, or the change in input commands to a beam positioner.

主权项

1. A method for providing radiation treatment to a patient having a body, the method comprising:
detecting, by a computer system, a position of each of a plurality of sensors of the patient's body at a current physical position of the body, the positions of the sensors being determined with respect to a reference point having a known spatial relationship to a radiation beam assembly, the radiation beam assembly configured to provide a radiation beam; determining, by the computer system, relative positions of the sensors with respect to each other; defining, by the computer system, a current multidimensional data point from the relative positions of the sensors, the current multidimensional data point corresponding to the current physical position of the body; using, by the computer system, a first mapping model that maps an input of the current multidimensional data point of the relative positions of the sensors to a current relative location of diseased tissue of the patient, the first mapping model determined from a plurality of multidimensional data points representing different physical positions of the patient's body having different locations of the diseased tissue, the current multidimensional data point being different than the plurality of multidimensional data points, the current relative location of the diseased tissue being relative to the positions of the sensors; and using the positions of the sensors and the current relative location of the diseased tissue to direct a radiation beam of the radiation beam assembly to the diseased tissue.