Dosage form to increase prasterone bioavailability

摘要

A way to formulate prasterone to both increase its oral bioavailability, and decrease the variability of its oral bioavailability.;
In contrast to the approach taught by the prior art, the instant approach is amenable to scale-up to commercial scale. Further, the resulting product is amenable to analysis using standard, known quantitative analytical techniques; thus, unlike the prior art approach, the instant approach may be used to manufacture a product in conformity with applicable regulatory standards.

主权项

1. A soft gelatin capsule suitable for oral administration, said soft gelatin capsule comprising:
A. a soft gelatin capsule, and B. a fill,
i. said fill consisting essentially of a durable oil vehicle, andii. at least about 100 milligrams of prasterone, and C. said soft gelatin capsule further having an outer lubricant coating.