Diagnostic test calibration adjustment method

摘要

A method is provided for adjusting either the signal measured or activity calculated by an instrument or a predefined calibration curve for a medical diagnostic test, performed on an instrument with pre-calibrated reagents. A calibration adjuster for a blood clotting diagnostic test is further provided.

主权项

1. A method for adjusting a signal measured for a blood clotting investigation test that is a dispersed solid phase immunological assay test, performed on an instrument with pre-calibrated reagents, comprising the following steps:
(i) defining a standard signal value, for one or two calibration adjuster(s) comprising a compound under test having a predetermined concentration or activity; (ii) measuring for said adjuster(s) a difference between the standard signal and the value of the signal measured by the instrument; (iii) adjusting the value of the signal measured by the instrument such that the value of the signal measured by the instrument is brought back to a signal value identical to the standard signal value determined in step (i) for the single adjuster or for each of the two adjusters; and (iv) applying the adjustment of step (iii) to each compound under test.