发明名称 |
Polynucleotides encoding recombinant C1 beta-glucosidase for production of sugars from cellulosic biomass |
摘要 |
The invention relates to expression of a recombinant C1 β-glucosidase. The invention also provides methods for producing a fermentable sugar from cellobiose by contacting celiobiose with a recombinant host cell comprising a polynucleotide sequence encoding C1 β-glucosidase, operably linked to heterologous promoter, under conditions in which β-glucosidase is expressed and secreted by the cell and the cellobiose is enzymatically converted by said β-glucosidase to glucose. Methods of the invention may be used for conversion of a biomass substrate to a fermentable sugar, and ultimately to ethanol or other biofuel. |
申请公布号 |
US8900847(B2) |
申请公布日期 |
2014.12.02 |
申请号 |
US201013496368 |
申请日期 |
2010.09.30 |
申请人 |
Codexis, Inc. |
发明人 |
Clark Louis;Baidyaroy Dipnath;Szabo Lorand |
分类号 |
C07H21/00;C12N15/00;C12P21/00;C12N1/21;C12N5/10;C12P19/14;C12N9/42;C12N9/24 |
主分类号 |
C07H21/00 |
代理机构 |
Codexis, Inc. |
代理人 |
Codexis, Inc. |
主权项 |
1. An isolated polynucleotide encoding a recombinant β-glucosidase polypeptide, wherein said isolated polynucleotide comprises SEQ ID NO:9. |
地址 |
Redwood City CA US |