| 发明名称 | Polyamine derivatives | ||
| 摘要 | Disclosed are compounds, compositions and methods for systemic and local delivery of biologically active molecules. | ||
| 申请公布号 | US8900621(B2) | 申请公布日期 | 2014.12.02 |
| 申请号 | US201313790980 | 申请日期 | 2013.03.08 |
| 申请人 | CLSN Laboratories, Inc. | 发明人 | Slobodkin Gregory;Congo Richard;Matar Majed;Fewell Jason;Anwer Khursheed;Sparks Brian Jeffery |
| 分类号 | A61F2/00;A61K47/16;A61K31/713;C07C233/38;C07C235/10;C07C235/60;A61K47/48;A61K9/127;C07D475/04;C07H15/10;C07K7/23;C07K7/64 | 主分类号 | A61F2/00 |
| 代理机构 | Sterne, Kessler, Goldstein & Fox PL.L.C. | 代理人 | Sterne, Kessler, Goldstein & Fox PL.L.C. |
| 主权项 | 1. A compound of the formula: wherein n1, n2, n3, and n4 are independently 1, 2, 3, or 4; X and X′ are independently a bond, oxygen, or nitrogen; R1 and R2 are independently C8-C25 hydrocarbon groups optionally containing from 1-4 double or triple bonds; and T1 and T2 are independently hydrogen or a targeting ligand; G1 and G2 are independently bond or a polymer moiety, where at least one of T1 and T2 is a targeting ligand. | ||
| 地址 | Wilmington DE US | ||