| 发明名称 | Disintegrating particle composition and orally rapidly disintegrating tablet | ||
| 摘要 | Disclosed is an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity. The orally rapidly disintegrating tablet, which has a good texture and taste, an appropriate hardness, and good disintegrating properties, can be produced by using a composition, which is prepared by dispersing, by spray-drying, an inorganic excipient and starch(es) in complex particles composed of mannitol and xylitol, in an orally rapidly disintegrating tablet. | ||
| 申请公布号 | US8900602(B2) | 申请公布日期 | 2014.12.02 |
| 申请号 | US201013389874 | 申请日期 | 2010.08.11 |
| 申请人 | Fuji Chemical Industry Co., Ltd. | 发明人 | Fujiwara Keiichi;Fukami Tadashi;Koizumi Haruka |
| 分类号 | A23L1/48;A61K47/26;A61K9/20;A61K31/5375;A61K9/00 | 主分类号 | A23L1/48 |
| 代理机构 | Wenderoth, Lind & Ponack, L.L.P. | 代理人 | Wenderoth, Lind & Ponack, L.L.P. |
| 主权项 | 1. A disintegrating particle composition, which is prepared by homogeneously dispersing inorganic excipient(s) and starch(es) in complex particles which are composed of mannitol and xylitol, wherein (a) the sum of mannitol and xylitol is 70 to 90 parts by weight; (b) the inorganic excipient(s) are in the amount of 2 to 15 parts by weight; (c) the starch(es) are in the amount of 5 to 25 parts by weight, and the total amount of the ingredients (a), (b) and (c) is 100 parts by weight, wherein the starch(es) are at least one selected from the group consisting of potato starch, flour starch, sticky rice starch, sweet potato starch, tapioca starch, rice starch, cornstarch and waxy cornstarch, andwherein the composition is obtained by a spraying method. | ||
| 地址 | Toyama JP | ||