Treatment of IBD and IBS using both probiotic bacteria and fermented cereal as treatment effectors

摘要

The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effector. The novel treatment strategy is capable of removing the symptoms of inflammatory bowel diseases regardless of a mild, moderate or severe stage of the disease.

主权项

1. A method of treating irritable bowel syndrome (IBS) in a human subject, the method comprising administering to the subject a fermented cereal comprising Lactobacillus plantarum cells of strain 299 or 299v, wherein the fermented cereal is administered in an amount providing at least 18 g (dry weight) of a fermented cereal and at least 1×1011 cfu of said Lactobacillus plantarum cells on a daily basis, and wherein the fermented cereal is administered for a period of time effective to reduce at least one symptom of IBS.