Amide dendrimer compositions

摘要

Amide compounds, amide polymers, compositions including amide compounds and amide polymers may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, amide compounds and amide polymers may include a core derived from an amide polyol and an organic polyacid or ester.

主权项

1. A pharmaceutical composition comprising
a) an amide compound represented by the following Formula V: wherein
R3 is independently represented by the following Formula II: wherein
p, q and r independently represent an integer from 0-2;R4 independently represents wherein
m independently represents an integer from 1-20;R5 independently represents a hydrogen radical; a substituted or un-substituted alkyl radical; a substituted or un-substituted aryl radical; or R5 and a neighboring R5 together represent a link or links comprising a residue of a crosslinking agent, a substituted or un-substituted alicyclic radical, a substituted or un-substituted aromatic radical, or a substituted or un-substituted heterocyclic radical; or R5 represents a link with another compound; b) a crosslinking agent or residue thereof; and c) a pharmaceutically acceptable excipient.