发明名称 DERIVADOS DE PROLINAMIDA COMO ANTAGONISTAS DE NK3
摘要 The present invention relates to a compound of formula I wherein R1, R2, R3, R4, R5, X, n, and o are as defined herein and to a pharmaceutically acceptable acid addition salt thereof which are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
申请公布号 BRPI0812447(A2) 申请公布日期 2014.12.02
申请号 BR2008PI12447 申请日期 2008.05.29
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BO HAN;HENNER KNUST;MATTHIAS NETTEKOVEN;HASANE RATNI;XIHAN WU
分类号 C07D207/16;A61K31/401;A61P25/16;A61P25/18;C07D401/06;C07D487/10 主分类号 C07D207/16
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