发明名称 Chemical compounds 251
摘要 The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.;
申请公布号 US8901307(B2) 申请公布日期 2014.12.02
申请号 US200913000138 申请日期 2009.07.02
申请人 AstraZeneca AB 发明人 Dakin Leslie;Dowling James Edward;Lamb Michelle;Read Jon;Zheng Xiaolan
分类号 C07D417/10;A61K31/454;C07D417/14;A61K31/427;C07D277/34;C07D417/06;A61K31/426 主分类号 C07D417/10
代理机构 代理人
主权项 1. A compound, or a pharmaceutically acceptable salt thereof, wherein the compound has the structure:
地址 Sodertalje SE