发明名称 Stabilized leukocytes and their use
摘要 A method of producing extremely stable leukocytes from human blood samples which are stable for long period of time under extraordinary temperature conditions. The method also relates to producing and stabilizing the leukocytes with formaldehyde release agents. The method is directed at the use of the stabilized leukocytes as a control in assays for determining CD4+ and HIV diagnosis and therapy.
申请公布号 US8900864(B2) 申请公布日期 2014.12.02
申请号 US201113825227 申请日期 2011.09.13
申请人 Nordrhein-Wesfalen Krankenhausbetriebsgesellschaft Bad Oeynhausen mbH 发明人 Prante Christian;Kleesiek Knut;Prohaska Wolfgang
分类号 C12N5/078;A01N1/02;G01N33/50;G01N33/569 主分类号 C12N5/078
代理机构 Davis & Bujold, PLLC 代理人 Davis & Bujold, PLLC ;Bujold Michael J.
主权项 1. An in-vitro method for stabilizing leukocytes, the method comprising the steps of: incubating leukocytes for at least 12 hours in a solution comprising a formaldehyde-releasing agent, followed by lyophilization of the incubation solution resulting in a long-term stable lyophilized preparation.
地址 Bad Oeynhausen DE