发明名称 |
Method for forming nerve graft |
摘要 |
A method for forming a nerve graft includes the following steps. A carbon nanotube structure is provided. A hydrophilic layer is formed on a surface of the carbon nanotube structure. The hydrophilic layer is polarized to form a polar surface on the hydrophilic layer. A number of neurons are formed on the polar surface of the hydrophilic layer to form a nerve network. The neurons connect with each other. |
申请公布号 |
US8900866(B2) |
申请公布日期 |
2014.12.02 |
申请号 |
US201213349577 |
申请日期 |
2012.01.13 |
申请人 |
Tsinghua University;Hon Hai Precision Industry Co., Ltd. |
发明人 |
Feng Chen;Fan Li;Zhao Wen-Mei |
分类号 |
C12N5/00;C12N5/02;A61L27/08;A61L27/34 |
主分类号 |
C12N5/00 |
代理机构 |
Novak Druce Connolly Bove + Quigg LLP |
代理人 |
Novak Druce Connolly Bove + Quigg LLP |
主权项 |
1. A method for forming a nerve graft, comprising:
providing a carbon nanotube structure; evaporating or sputtering an inorganic material on a surface of the carbon nanotube structure to form a hydrophilic layer; soaking the hydrophilic layer with a polyamino acid solution or a polyetherimide solution to polarize a surface of the hydrophilic layer to a polar surface, wherein the soaking the hydrophilic layer with the polyamino acid solution or the polyetherimide solution comprises sub-steps of:
providing a supporter;placing the carbon nanotube structure having the hydrophilic layer on a surface of the supporter; andsoaking the hydrophilic layer on the carbon nanotube structure on the surface of the supporter with the polyamino acid solution or the polyetherimide solution to polarize a surface of the hydrophilic layer to a polar surface; andcompletely removing the polyamino acid solution or the polyetherimide solution from the polar surface; and seeding and culturing a plurality of neurons on the polar surface until adjacent neurons of the plurality of neurons are connected with each other, and the plurality of neurons form a nerve network. |
地址 |
Beijing CN |