发明名称 Processes for the manufacture of a pharmaceutically active agent
摘要 Disclosed herein are processes for the preparation of a pharmaceutically active agent and pharmaceutically acceptable salts thereof.
申请公布号 US8901318(B2) 申请公布日期 2014.12.02
申请号 US201313875623 申请日期 2013.05.02
申请人 H. Lundbeck A/S 发明人 Therkelsen Frans;Rock Michael Harold;Treppendahl Svend
分类号 C07D209/16;C07D209/14 主分类号 C07D209/16
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A process for the preparation of a compound of formula II comprising the steps of: (a) mixing a solution of diethoxymethane, water and formic acid; (b) adding the solution of step (a) to a mixture of 6-fluoroindole, dimethylamine and acetic acid; and (c) adding an aqueous basic solution.
地址 Copenhagen-Valby DK