发明名称 |
Processes for the manufacture of a pharmaceutically active agent |
摘要 |
Disclosed herein are processes for the preparation of a pharmaceutically active agent and pharmaceutically acceptable salts thereof. |
申请公布号 |
US8901318(B2) |
申请公布日期 |
2014.12.02 |
申请号 |
US201313875623 |
申请日期 |
2013.05.02 |
申请人 |
H. Lundbeck A/S |
发明人 |
Therkelsen Frans;Rock Michael Harold;Treppendahl Svend |
分类号 |
C07D209/16;C07D209/14 |
主分类号 |
C07D209/16 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A process for the preparation of a compound of formula II comprising the steps of: (a) mixing a solution of diethoxymethane, water and formic acid; (b) adding the solution of step (a) to a mixture of 6-fluoroindole, dimethylamine and acetic acid; and (c) adding an aqueous basic solution. |
地址 |
Copenhagen-Valby DK |