发明名称 |
Morpholino pyrimidines and their use in therapy |
摘要 |
<p>The disclosure relates to pyrimidinyl compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification. The disclosure also provides processes for their preparation, pharmaceutical compositions containing them and their use in therapy. These compounds are suitable for the treatment of cancer or for the prevention or treatment of those tumours which are sensitive to inhibition of ATR kinase.</p> |
申请公布号 |
NZ604480(A) |
申请公布日期 |
2014.11.28 |
申请号 |
NZ20110604480 |
申请日期 |
2011.06.09 |
申请人 |
ASTRAZENECA AB |
发明人 |
FOOTE KEVIN MICHAEL;NISSINK JOHANNES WILHELMUS MARIA;TURNER PAUL |
分类号 |
A61K31/505;A61P35/00;C07D413/14;C07D471/04 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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