NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIAL MEDICAMENTS

摘要

THE INVENTION CONCERNS NITROGENATED HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL DRUGS, COMPOUNDS OF GENERAL FORMULA (I) WHEREIN R1 REPRESENTS A (CH2)N-NH2 OR (CH2)N-NHR RADICAL, WHERE R IS A (C1?C6) ALKYL AND N IS EQUAL TO 1 OR 2; R2 REPRESENTS A HYDROGEN ATOM; R3 AND R4 TOGETHER FORM AN AROMATIC NITROGENATED HETEROCYCLE WITH 5 APEXES WITH 1, 2 OR 3 NITROGEN ATOMS OPTIONALLY SUBSTITUTED BY ONE OR SEVERAL R? GROUPS, R? BEING SELECTED IN THE GROUP COMPOSED OF A HYDROGEN ATOM AND ALKYL RADICALS WITH 1 TO 6 CARBON ATOMS; IN FREE FORM, AS ZWITTERIONS, AND IN THE FORM OF SALTS OF PHARMACEUTICALLY ACCEPTABLE INORGANIC OR ORGANIC BASES AND ACIDS.